Yes. The way that data bundles work means they have a home country and roaming countries. Below are some examples of how this works.
If you require data coverage in the United Kingdom but also wanted coverage in Germany. You can buy a data bundle for the United Kingdom which then uses Germany as a roaming country. This bundle will therefore work in both countries with no extra charge.
If you require data coverage in the United Kingdom but also wanted coverage in South Africa. You can buy a data bundle for South Africa which then uses the United Kingdom as a roaming country. This bundle will therefore work in both countries and at no extra charge.
You can have two bundles that run parallel with each other at the same time.
If you have an Asia and a Europe regional bundle applied. The eSIM will always use the appropriate bundle for the destination you are in.